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Mouse models of autoimmune disease suggest that self-tolerance is maintained by unresponsive autoreactive T cells.

Multiple organ-localized autoimmune diseases, such as thyroiditis and gastritis, spontaneously develop in BALB/c nu/nu (nude) mice receiving embryonic rat thymus grafts (TG) under their renal capsules (TG nude mice). When thyroid was grafted into the rat thymus of TG nude mice, development of autoim...

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Dettagli Bibliografici
Autori principali: Taguchi, O, Takahashi, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456664/
https://ncbi.nlm.nih.gov/pubmed/8911134
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