Pharmacological modulation of activation-secretion of rat serosal mast cells by chymase, an endogenous secretory granule protease.

The action of pharmacologic agents on chymase-induced exocytosis of beta-hexosaminidase and arachidonic acid (AA) metabolism by rat serosal mast cells (RSMC) was determined and compared with their effects on anti-IgE induced activation. Indomethacin (INDO) (less than or equal to 10 microM), a cycloo...

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Bibliographic Details
Main Authors: Schick, B, Austen, K F
Format: Artigo
Language:Inglês
Published: 1985
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1453738/
https://ncbi.nlm.nih.gov/pubmed/3935569
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