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The Coupon Collector and the Suppressor Mutation: Estimating the Number of Compensatory Mutations by Maximum Likelihood
Compensatory mutation occurs when a loss of fitness caused by a deleterious mutation is restored by its epistatic interaction with a second mutation at a different site in the genome. How many different compensatory mutations can act on a given deleterious mutation? Although this quantity is fundame...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1451182/ https://ncbi.nlm.nih.gov/pubmed/15879511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.037259 |
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