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Evaluation of absolute quantitation by nonlinear regression in probe-based real-time PCR

BACKGROUND: In real-time PCR data analysis, the cycle threshold (CT) method is currently the gold standard. This method is based on an assumption of equal PCR efficiency in all reactions, and precision may suffer if this condition is not met. Nonlinear regression analysis (NLR) or curve fitting has...

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Main Authors: Goll, Rasmus, Olsen, Trine, Cui, Guanglin, Florholmen, Jon
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450306/
https://ncbi.nlm.nih.gov/pubmed/16515700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-107
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