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Dextran sulphate: a synthetic activator of C3 via the alternative pathway. I. Influence of molecular size and degree of sulphation on the activation potency.
The polyanion dextran sulphate (DS) triggers the alternative pathway of complement. The influence of the molecular weight and degree of sulphation on this potency was studied. The degree of substitution turned out to be the critical parameter for optimal C3 turnover: 60 SO4/100 glucose units (Glc) s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1975
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1445957/ https://ncbi.nlm.nih.gov/pubmed/1172484 |
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