Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin

Focal segmental glomerulosclerosis (FSGS) is the most common primary glomerular diagnosis resulting in end-stage renal disease. Defects in several podocyte proteins have been implicated in the etiology of FSGS, including podocin, α-actinin–4, CD2-associated protein (CD2AP), and TRPC6. Despite our gr...

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Main Authors: Huber, Tobias B., Kwoh, Christopher, Wu, Hui, Asanuma, Katsuhiko, Gödel, Markus, Hartleben, Björn, Blumer, Ken J., Miner, Jeffrey H., Mundel, Peter, Shaw, Andrey S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440708/
https://ncbi.nlm.nih.gov/pubmed/16628251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27400
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