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Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ

INTRODUCTION: Ductal carcinoma in situ (DCIS) is a noninvasive premalignant lesion and is considered a precursor to invasive carcinoma. DCIS accounts for nearly 20% of newly diagnosed breast cancer, but the lack of experimentally amenable in vivo DCIS models hinders the development of treatment stra...

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Autors principals: Namba, Ruria, Young, Lawrence JT, Maglione, Jeannie E, McGoldrick, Erik T, Liu, Stephenie, Wurz, Gregory T, DeGregorio, Michael W, Borowsky, Alexander D, MacLeod, Carol L, Cardiff, Robert D, Gregg, Jeffrey P
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410776/
https://ncbi.nlm.nih.gov/pubmed/16280035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1317
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