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A pharmacokinetic interaction in man between phenobarbitone and fenoprofen, a new anti-inflammatory agent

1 The effect of repeated administration of phenobarbitone on the plasma disposition of fenoprofen (±-2-(3-phenoxyphenyl) propionic acid) was investigated in rats and man. 2 The plasma elimination rate constants increased significantly and the rats excreted proportionately more metabolized fenoprofen...

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Autori principali: Helleberg, L., Rubin, A., Wolen, R. L., Rodda, B. E., Ridolfo, A. S., Gruber, C. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1974
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402462/
https://ncbi.nlm.nih.gov/pubmed/22454912
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