A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase

Cell motility is a complex biological process, involved in development, inflammation, homeostasis, and pathological processes such as the invasion and metastatic spread of cancer. Here, we describe a genomic screen designed to identify inhibitors of cell migration. A library of 10,996 small interfer...

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Bibliografske podrobnosti
Main Authors: Collins, Cynthia S., Hong, Jiyong, Sapinoso, Lisa, Zhou, Yingyao, Liu, Zheng, Micklash, Kenneth, Schultz, Peter G., Hampton, Garret M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383649/
https://ncbi.nlm.nih.gov/pubmed/16537454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600040103
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