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The effect of tocainide on theophylline metabolism.
The effect of 5 days of oral tocainide (400 mg every 8 h) on the kinetics of theophylline given as a single 5 mg kg-1 i.v. infusion over 30 min was investigated in eight healthy male nonsmokers. Treatment with tocainide decreased the plasma clearance of theophylline from 37.5 +/- 6.9 (mean +/- s.d.)...
Tallennettuna:
Päätekijät: | , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
1993
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1381557/ https://ncbi.nlm.nih.gov/pubmed/8485025 |
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