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Methods for detection of parent-of-origin effects in genetic studies of case-parents triads.
When affected probands and their biological parents are genotyped at a candidate gene or a marker, the resulting case-parents-triad data enable powerful tests for linkage in the presence of association. When linkage disequilibrium has been detected in such a study, the investigator may wish to look...
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Hovedforfatter: | |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
1999
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1378094/ https://ncbi.nlm.nih.gov/pubmed/10364536 |
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