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Familial progressive sensorineural deafness is mainly due to the mtDNA A1555G mutation and is enhanced by treatment of aminoglycosides.

Hearing loss involves both genetic and environmental factors. A mutation (A1555G) in the mtDNA has been associated with aminoglycoside-induced and nonsyndromic sensorineural deafness. The pathological significance of this mutation in Caucasoid families has not been established, and its relationship...

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Detalhes bibliográficos
Main Authors: Estivill, X, Govea, N, Barceló, E, Badenas, C, Romero, E, Moral, L, Scozzri, R, D'Urbano, L, Zeviani, M, Torroni, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1376822/
https://ncbi.nlm.nih.gov/pubmed/9490575
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