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Multivariate curve resolution: a powerful tool for the analysis of conformational transitions in nucleic acids
A successful application is reported of the multivariate curve resolution alternating least-squares method (MCR-ALS) for the analysis of nucleic acid melting and salt-induced transitions. Under conditions where several structures co-exist in a conformational equilibrium, MCR-ALS analysis of the UV a...
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Autors principals: | , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Oxford University Press
2002
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137437/ https://ncbi.nlm.nih.gov/pubmed/12202780 |
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