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Multivariate curve resolution: a powerful tool for the analysis of conformational transitions in nucleic acids

A successful application is reported of the multivariate curve resolution alternating least-squares method (MCR-ALS) for the analysis of nucleic acid melting and salt-induced transitions. Under conditions where several structures co-exist in a conformational equilibrium, MCR-ALS analysis of the UV a...

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Autors principals: Jaumot, Joaquim, Escaja, Núria, Gargallo, Raimundo, González, Carlos, Pedroso, Enrique, Tauler, Romà
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC137437/
https://ncbi.nlm.nih.gov/pubmed/12202780
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