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Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs
Lipopolysaccharide (LPS) stimulates production of inflammatory mediators, partly by stabilizing [interleukin-6 (IL-6), cyclooxygenase 2 (COX-2)] and/or stimulating translation [tumour necrosis factor-α (TNF-α)] of their mRNAs. Such regulation depends on AU-rich elements (AREs) within the 3′-untransl...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2002
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136943/ https://ncbi.nlm.nih.gov/pubmed/12456657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf639 |
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