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Conditional mutants of the yeast mRNA capping enzyme show that the cap enhances, but is not required for, mRNA splicing.
The 5' end of eukaryotic mRNAs are modified by the addition of a 7-methyl guanosine (m7G) cap. The role of the cap in translation has been well established. Additionally, studies conducted in vitro or in microinjected Xenopus oocytes have implicated the cap in RNA processing and transport. To d...
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Hauptverfasser: | , |
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Format: | Artigo |
Sprache: | Inglês |
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1996
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1369397/ https://ncbi.nlm.nih.gov/pubmed/8718687 |
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