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Poliovirus Internal Ribosome Entry Segment Structure Alterations That Specifically Affect Function in Neuronal Cells: Molecular Genetic Analysis

Translation of poliovirus RNA is driven by an internal ribosome entry segment (IRES) present in the 5′ noncoding region of the genomic RNA. This IRES is structured into several domains, including domain V, which contains a large lateral bulge-loop whose predicted secondary structure is unclear. The...

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Autors principals: Malnou, Cécile E., Pöyry, Tuija A. A., Jackson, Richard J., Kean, Katherine M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC136602/
https://ncbi.nlm.nih.gov/pubmed/12368304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.10617-10626.2002
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