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Reconciling the working strokes of a single head of skeletal muscle myosin estimated from laser-trap experiments and crystal structures

Myosin generates force by a rotation of its lever arm. Crystal structures of myosin II indicate an unloaded working stroke of 10–12 nm, a range confirmed by recent x-ray interference experiments. However, when an actin filament, held between two weakly, optically trapped beads is made to interact wi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sleep, John, Lewalle, Alexandre, Smith, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360521/
https://ncbi.nlm.nih.gov/pubmed/16428290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506272103
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