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Reconciling the working strokes of a single head of skeletal muscle myosin estimated from laser-trap experiments and crystal structures
Myosin generates force by a rotation of its lever arm. Crystal structures of myosin II indicate an unloaded working stroke of 10–12 nm, a range confirmed by recent x-ray interference experiments. However, when an actin filament, held between two weakly, optically trapped beads is made to interact wi...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
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National Academy of Sciences
2006
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1360521/ https://ncbi.nlm.nih.gov/pubmed/16428290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506272103 |
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