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Anti-Endotoxin Agents. 2. Pilot High-Throughput Screening for Novel Lipopolysaccharide-Recognizing Motifs in Small Molecules

Lipopolysaccharides (LPS), otherwise termed ‘endotoxins’, are an integral part of the outer leaflet of the outer-membrane of Gram-negative bacteria. Lipopolysaccharides play a pivotal role in the pathogenesis of ‘Septic Shock’, a major cause of mortality in the critically ill patient, worldwide. The...

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Hlavní autoři: Wood, Stewart J., Miller, Kelly A., David, Sunil A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360204/
https://ncbi.nlm.nih.gov/pubmed/15578935
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