Herpes Simplex Virus-based gene Therapy Enhances the Efficacy of Mitomycin-C in the Treatment of Human Bladder Transitional Cell Carcinoma

PURPOSE: Oncolytic replication-competent herpes simplex virus type-1 (HSV) mutants have the ability to replicate in and kill malignant cells. We have previously demonstrated the ability of replication-competent HSV to control bladder cancer growth in an orthotopic murine model. We hypothesized that...

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Bibliographic Details
Main Authors: Mullerad, Michael, Bochner, Bernard H., Adusumilli, Prasad S., Bhargava, Amit, Kikuchi, Eiji, Hui-Ni, Chen, Kattan, Michael W., Chou, Ting-Chao, Fong, Yuman
Format: Artigo
Language:Inglês
Published: 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351159/
https://ncbi.nlm.nih.gov/pubmed/16006968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.ju.0000164730.38431.5c
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