Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide

Endothelial dysfunction (ED) is an early feature of cardiovascular risk and diabetes. Hyperglycemia and hyperlipidemia are causative factors. Excessive endothelial mitochondrial superoxide (ROS) production with hyperglycemia and hyperlipidemia is a key mechanism. Inositol components of an insulin in...

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Bibliografske podrobnosti
Main Authors: Nascimento, N. R. F., Lessa, L. M. A., Kerntopf, M. R., Sousa, C. M., Alves, R. S., Queiroz, M. G. R., Price, J., Heimark, D. B., Larner, J., Du, X., Brownlee, M., Gow, A., Davis, C., Fonteles, M. C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1325005/
https://ncbi.nlm.nih.gov/pubmed/16373499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509779103
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