Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide

Endothelial dysfunction (ED) is an early feature of cardiovascular risk and diabetes. Hyperglycemia and hyperlipidemia are causative factors. Excessive endothelial mitochondrial superoxide (ROS) production with hyperglycemia and hyperlipidemia is a key mechanism. Inositol components of an insulin in...

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Bibliographic Details
Main Authors: Nascimento, N. R. F., Lessa, L. M. A., Kerntopf, M. R., Sousa, C. M., Alves, R. S., Queiroz, M. G. R., Price, J., Heimark, D. B., Larner, J., Du, X., Brownlee, M., Gow, A., Davis, C., Fonteles, M. C.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1325005/
https://ncbi.nlm.nih.gov/pubmed/16373499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509779103
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