Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CD(pro)

Poliovirus protein 3CD(pro )possesses both proteinase and RNA binding activities, which are located in the 3C(pro )domain of the protein. The RNA polymerase (3D(pol)) domain of 3CD(pro )modulates these activities of the protein. We have recently shown that the level of 3CD(pro )in HeLa cell-free in...

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Main Authors: Franco, David, Pathak, Harsh B, Cameron, Craig E, Rombaut, Bart, Wimmer, Eckard, Paul, Aniko V
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2005
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315353/
https://ncbi.nlm.nih.gov/pubmed/16300678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-2-86
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