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Purification and Functional Reconstitution of N- and C-Halves of the MscL Channel

MscL is a mechanosensitive channel gated by membrane tension in the lipid bilayer alone. Its structure, known from x-ray crystallography, indicates that it is a homopentamer. Each subunit comprises two transmembrane segments TM1 and TM2 connected by a periplasmic loop. The closed pore is lined by fi...

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Autori principali: Park, Kyu-Ho, Berrier, Catherine, Martinac, Boris, Ghazi, Alexandre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304064/
https://ncbi.nlm.nih.gov/pubmed/15041653
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