Are experimental treatments for cancer in children superior to established treatments? Observational study of randomised controlled trials by the Children's Oncology Group

Objectives To assess how often new treatments for childhood cancer assessed in phase III randomised trials are superior or inferior to standard treatments and whether the pattern of successes and failures in new treatments is consistent with uncertainty being the ethical basis for enrolling patients...

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Main Authors: Kumar, Ambuj, Soares, Heloisa, Wells, Robert, Clarke, Mike, Hozo, Iztok, Bleyer, Archie, Reaman, Gregory, Chalmers, Iain, Djulbegovic, Benjamin
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group Ltd. 2005
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Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1298846/
https://ncbi.nlm.nih.gov/pubmed/16299015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmj.38628.561123.7C
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