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Are experimental treatments for cancer in children superior to established treatments? Observational study of randomised controlled trials by the Children's Oncology Group

Objectives To assess how often new treatments for childhood cancer assessed in phase III randomised trials are superior or inferior to standard treatments and whether the pattern of successes and failures in new treatments is consistent with uncertainty being the ethical basis for enrolling patients...

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Bibliografiske detaljer
Main Authors: Kumar, Ambuj, Soares, Heloisa, Wells, Robert, Clarke, Mike, Hozo, Iztok, Bleyer, Archie, Reaman, Gregory, Chalmers, Iain, Djulbegovic, Benjamin
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group Ltd. 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1298846/
https://ncbi.nlm.nih.gov/pubmed/16299015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmj.38628.561123.7C
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