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Melanocortin-1 Receptor Polymorphisms and Risk of Melanoma: Is the Association Explained Solely by Pigmentation Phenotype?

Risk of cutaneous malignant melanoma (CMM) is increased in sun-exposed whites, particularly those with a pale complexion. This study was designed to investigate the relationship of the melanocortin-1 receptor (MC1R) genotype to CMM risk, controlled for pigmentation phenotype. We report the occurrenc...

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Autors principals: Palmer, James S., Duffy, David L., Box, Neil F., Aitken, Joanne F., O'Gorman, Louise E., Green, Adele C., Hayward, Nicholas K., Martin, Nicholas G., Sturm, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Human Genetics 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288324/
https://ncbi.nlm.nih.gov/pubmed/10631149
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