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Cyclo-oxygenase-2 contributes to constitutive prostanoid production in rat kidney and brain
Cyclo-oxygenases (COXs) catalyse the synthesis of PGH(2) (prostaglandin H(2)), which serves as the common substrate for the production of PGE(2), PGD(2), PGF(2α), prostacyclin (or PGI(2)) and TXs (thromboxanes). While COX-1 is the major isoform responsible for prostanoid synthesis in healthy tissues...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1276956/ https://ncbi.nlm.nih.gov/pubmed/16008526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050451 |
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