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A Novel Method with Improved Power To Detect Recombination Hotspots from Polymorphism Data Reveals Multiple Hotspots in Human Genes

We introduce a new method for detection of recombination hotspots from population genetic data. This method is based on (a) defining an (approximate) penalized likelihood for how recombination rate varies with physical position and (b) maximizing this penalized likelihood over possible sets of recom...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Fearnhead, Paul , Smith, Nick G. C. 
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Human Genetics 2005
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271387/
https://ncbi.nlm.nih.gov/pubmed/16252238
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