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Bacterial senescence: protein oxidation in non-proliferating cells is dictated by the accuracy of the ribosomes

We have investigated the causal factors behind the age-related oxidation of proteins during arrest of cell proliferation. A proteomic approach demonstrated that protein oxidation in non-proliferating cells is observed primarily for proteins being produced in a number of aberrant isoforms. Also, thes...

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Autors principals: Ballesteros, Manuel, Fredriksson, Åsa, Henriksson, Jaqueline, Nyström, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC125621/
https://ncbi.nlm.nih.gov/pubmed/11566891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.18.5280
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