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Pharmacokinetics of toxic chemicals in breast milk: use of PBPK models to predict infant exposure.

Factors controlling the transfer of potentially toxic chemicals in the breast milk of nursing mothers include both chemical characteristics, such as lipophilicity, and physiologic changes during lactation. Physiologically based pharmacokinetic (PBPK) models can aid in the prediction of infant exposu...

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Bibliographic Details
Main Authors: Clewell, Rebecca A, Gearhart, Jeffery M
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1240887/
https://ncbi.nlm.nih.gov/pubmed/12055064
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