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Molecular and biochemical characterization of two P450 enzymes in the ecdysteroidogenic pathway of Drosophila melanogaster

Five different enzymatic activities, catalyzed by both microsomal and mitochondrial cytochrome P450 monooxygenases (CYPs), are strongly implicated in the biosynthesis of ecdysone (E) from cholesterol. However, none of these enzymes have been characterized completely. The present data show that the w...

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Main Authors: Warren, James T., Petryk, Anna, Marqués, Guillermo, Jarcho, Michael, Parvy, Jean-Philippe, Dauphin-Villemant, Chantal, O'Connor, Michael B., Gilbert, Lawrence I.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC123207/
https://ncbi.nlm.nih.gov/pubmed/12177427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162375799
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