Activator protein-2gamma (AP-2gamma) expression is specifically induced by oestrogens through binding of the oestrogen receptor to a canonical element within the 5'-untranslated region.

The activator protein 2 (AP-2) transcription factors are essential proteins for oestrogenic repression of the ERBB2 proto-oncogene in breast cancer cells. In the present study, we have examined the possible oestrogenic regulation of AP-2 genes themselves in breast-tumour-derived lines. As early as 1...

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Bibliographic Details
Main Authors: Orso, Francesca, Cottone, Erika, Hasleton, Mark D, Ibbitt, J Claire, Sismondi, Piero, Hurst, Helen C, De Bortoli, Michele
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223884/
https://ncbi.nlm.nih.gov/pubmed/14565844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031133
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