Decreased activity and enhanced nuclear export of CCAAT-enhancer-binding protein beta during inhibition of adipogenesis by ceramide.

To identify novel molecular mechanisms by which ceramide regulates cell differentiation, we examined its effect on adipogenesis of 3T3-L1 preadipocytes. Hormonal stimulation of 3T3-L1 preadipocytes induced formation of triacylglycerol-laden adipocytes over 7 days; in part, via the co-ordinated actio...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Sprott, Kam M, Chumley, Michael J, Hanson, Janean M, Dobrowsky, Rick T
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2002
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222668/
https://ncbi.nlm.nih.gov/pubmed/12071851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020215
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