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Replication of HIV-1 viruses in the presence of the Portland alpha1-antitrypsin variant (alpha1-PDX) inhibitor.
The Portland alpha1-antitrypsin variant (alpha1-PDX) inhibits gp160 cleavage into gp120 and gp41 by different prohormone convertases (PCs) including furin, PC5 and PC7. Jurkat cells stably transfected with this inhibitor (J-PDX cells) and, as controls, Jurkat cells transfected with the empty vector...
Kaydedildi:
Asıl Yazarlar: | , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2001
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1222209/ https://ncbi.nlm.nih.gov/pubmed/11695999 |
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