Bi-directional effects of the elevation of intracellular calcium on the expression of inducible nitric oxide synthase in J774 macrophages exposed to low and to high concentrations of endotoxin.

Nitric oxide produced through the action of inducible nitric oxide synthase (iNOS) is an important mediator in immune responses of the host. Various extracellular factors, including inflammatory stimuli, affect intracellular free Ca2+ levels ([Ca2+](i)), modulating cellular signalling and gene expre...

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Hauptverfasser: Korhonen, R, Kankaanranta, H, Lahti, A, Lähde, M, Knowles, R G, Moilanen, E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221663/
https://ncbi.nlm.nih.gov/pubmed/11171114
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