Transcriptional regulation of the human asparagine synthetase gene by carbohydrate availability.

Eitemau Tebyg

• Multiple adaptive mechanisms affect asparagine synthetase substrate availability in asparaginase-resistant MOLT-4 human leukaemia cells.
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• Asparagine Synthetase Chemotherapy
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• Alignment of the Transcription Start Site Coincides with Increased Transcriptional Activity from the Human Asparagine Synthetase Gene Following Amino Acid Deprivation of HepG2 Cells()
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• Asparagine synthetase: regulation by cell stress and involvement in tumor biology
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• C/EBP Homology Protein (CHOP) Interacts with Activating Transcription Factor 4 (ATF4) and Negatively Regulates the Stress-dependent Induction of the Asparagine Synthetase Gene
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  Cyhoeddwyd: (2008)