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Expression of extracellular matrix molecules in human mesangial cells in response to prolonged hyperglycaemia.

Post-mitotic cultures of human mesangial cells were maintained in media containing 4-30 mM D-glucose for up to 28 days. Changes in mRNA and protein levels for specific macromolecules occurred between 7 and 14 days after initiating hyperglycaemic conditions. Slot blot analysis showed 2-3-fold increas...

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Bibliographic Details
Main Authors: Wahab, N A, Harper, K, Mason, R M
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217445/
https://ncbi.nlm.nih.gov/pubmed/8670179
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