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Cold-induced reduction in Gi alpha proteins in brown adipose tissue. Effects on the cellular hypersensitization to noradrenaline caused by pertussis-toxin treatment.

The significance of Gi proteins for the physiological desensitization phenomena observed in brown-fat cells from cold-acclimated hamsters was investigated. For this purpose, pertussis toxin (the inhibitor of Gi function) was injected into control and cold-acclimated hamsters. After 3 days the thermo...

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Bibliographic Details
Main Authors: Svoboda, P, Unelius, L, Dicker, A, Cannon, B, Milligan, G, Nedergaard, J
Format: Artigo
Language:Inglês
Published: 1996
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217122/
https://ncbi.nlm.nih.gov/pubmed/8615767
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