An Implanted Recombination Hot Spot Stimulates Recombination and Enhances Sister Chromatid Cohesion of Heterologous Yacs during Yeast Meiosis

Heterologous yeast artificial chromosomes (YACs) do not recombine with each other and missegregate in 25% of meiosis I events. Recombination hot spots in the yeast Saccharomyces cerevisiae have previously been shown to be associated with sites of meiosis-induced double-strand breaks (DSBs). A 6-kb f...

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Main Authors: Sears, D. D., Hieter, P., Simchen, G.
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1206247/
https://ncbi.nlm.nih.gov/pubmed/7896090
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