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Tuning genetic control through promoter engineering
Gene function is typically evaluated by sampling the continuum of gene expression at only a few discrete points corresponding to gene knockout or overexpression. We argue that this characterization is incomplete and present a library of engineered promoters of varying strengths obtained through muta...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1200280/ https://ncbi.nlm.nih.gov/pubmed/16123130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504604102 |
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