Differential block of sodium and calcium channels by chlorpromazine in mouse neuroblastoma cells.

1. The effects of chlorpromazine on the voltage-activated sodium and type I (transient) calcium channels were studied in cultured mouse neuroblastoma cells (N1E-115) using the whole-cell patch-clamp technique. 2. Chlorpromazine (2-10 x 10(-6) M) blocked both the sodium channel current and the calciu...

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Bibliographic Details
Main Authors: Ogata, N, Yoshii, M, Narahashi, T
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190043/
https://ncbi.nlm.nih.gov/pubmed/2157837
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