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Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons.

1. We have examined the effect of picrotoxin on GABA-induced currents in dissociated rat hippocampal neurons. In addition, we used the putative picrotoxin receptor antagonist, alpha-isopropyl-alpha-methyl-gamma-butyrolactone (alpha IMGBL), and the picrotoxin agonist, beta-ethyl-beta-methyl-gamma-but...

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Bibliographic Details
Main Authors: Yoon, K W, Covey, D F, Rothman, S M
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175394/
https://ncbi.nlm.nih.gov/pubmed/8229811
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