mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila.

Dosage compensation is a regulatory process that insures that males and females have equal amounts of X-chromosome gene products. In Drosophila, this is achieved by a 2-fold enhancement of X-linked gene transcription in males, relative to females. The enhancement of transcription is mediated by the...

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Hlavní autoři: Hilfiker, A, Hilfiker-Kleiner, D, Pannuti, A, Lucchesi, J C
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169808/
https://ncbi.nlm.nih.gov/pubmed/9155031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.8.2054
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