Rearrangement of immunoglobulin heavy chain genes in human T leukaemic cells shows preferential utilization of the D segment (DQ52) nearest to the J region.

The DNA rearrangements leading to the assembly of genes coding for the immunoglobulin heavy chain (IgH) in B cells and the T cell receptor for antigen in T cells are not completely lineage specific. This probably reflects the use of a common recombinase by IgH and the T cell receptor. This paper des...

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Main Authors: Mizutani, S, Ford, A M, Wiedemann, L M, Chan, L C, Furley, A J, Greaves, M F, Molgaard, H V
格式: Artigo
語言:Inglês
出版: 1986
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1167382/
https://ncbi.nlm.nih.gov/pubmed/3030728
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