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Effect of tunicamycin on the metabolism of low-density lipoproteins by control and low-density-lipoprotein-receptor-deficient human skin fibroblasts.
Preincubation of normal human skin fibroblasts with tunicamycin, which inhibits N-glycosylation of glycoproteins, resulted in a dose-dependent and reversible inhibition of binding and internalization of homologous low-density lipoproteins by the cells. The degradation of the internalized lipoprotein...
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Main Authors: | , |
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Format: | Artigo |
Language: | Inglês |
Published: |
1980
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1161540/ https://ncbi.nlm.nih.gov/pubmed/7370019 |
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