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Reversible reduction of insulin receptor affinity by ATP depletion in rat adipocytes.

The effects of the metabolic inhibitor NaN3 on insulin receptors in isolated rat fat-cells were investigated. The agent reduced insulin binding in parallel to a decrease of the ATP content of cells. Both effects were observed in the same concentration range of NaN3, and were fully reversible. Accord...

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Sonraí Bibleagrafaíochta
Main Authors: Steinfelder, H J, Joost, H G
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1983
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1152227/
https://ncbi.nlm.nih.gov/pubmed/6351848
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