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Intact MutY and its catalytic domain differentially contact with A/8-oxoG-containing DNA
Escherichia coli MutY is an adenine and a weak guanine DNA glycosylase active on DNA substrates containing A/G, A/8-oxoG, A/C or G/8-oxoG mismatches. A truncated form of MutY (M25, residues 1–226) retains catalytic activity; however, the C-terminal domain of MutY is required for specific binding to...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC115170/ https://ncbi.nlm.nih.gov/pubmed/11095667 |
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