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Down-regulation of mannose receptors on macrophages after infection with Leishmania donovani.
Macrophages express a mannose-specific endocytosis receptor that binds and internalizes mannose-terminated glycoproteins. Infection of mouse peritoneal macrophages with Leishmania donovani resulted in a decrease in mannose-receptor activity. With 125I-labelled beta-glucuronidase as ligand, a 2-fold...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
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1991
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1151255/ https://ncbi.nlm.nih.gov/pubmed/1859373 |
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