Copper + zinc and manganese superoxide dismutases inhibit deoxyribose degradation by the superoxide-driven Fenton reaction at two different stages. Implications for the redox states of copper and manganese.

When OH. radicals are formed in a superoxide-driven Fenton reaction, in which O2.- is generated enzymically, deoxyribose degradation is effectively inhibited by CuZn- and Mn-superoxide dismutases. The products of this reaction are H2O2 and a Fe3+-EDTA chelate. The mixing of H2O2 and a Fe3+-EDTA chel...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gutteridge, J M, Bannister, J V
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1986
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1146550/
https://ncbi.nlm.nih.gov/pubmed/3010953
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