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A study of the mechanism by which some amphiphilic drugs affect human erythrocyte acetylcholinesterase activity.
The effects of the local anaesthetics procaine, tetracaine and lidocaine and of the antidepressant imipramine on human erythrocyte acetylcholinesterase were investigated. All four amphiphilic drugs inhibited enzymic activity, the IC50 (the concentration causing 50% inhibition) being about 0.40 mM fo...
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主要な著者: | , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
1989
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1138862/ https://ncbi.nlm.nih.gov/pubmed/2775233 |
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